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If you are taking such medicines as nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, or amyl nitrate, it's not suggested to take Tadalafil. Tadalafil (Cialis) is a male impotence drug that comes in tablets including 5, 10 and 20 mg. tadalafil soft tablets 10 mg is FDA pregnancy group B, although it is not planned for the use in women. This time period is not strict - in lots of guys Tadalafil remains effective for 36 hrs, and you can get involved into sex-related task throughout this whole period.